Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation
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چکیده
منابع مشابه
Identification of target genes of the p16INK4A-pRB-E2F pathway.
Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of human cancer. The core members of this pathway include the tumor suppressor protein, pRB, which through binding to a number of cellular proteins, most notably members of the E2F transcription factor family, regulates progression through the cell division cycle. With the aim of identifying transcriptional changes provoked ...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2012
ISSN: 1058-8388
DOI: 10.1002/dvdy.23857